49ers vs Buffalo Bills Match Player Stats Analysis
The 49ers vs buffalo bills match player stats tell the full story of a game that looked competitive on paper but turned into a one-sided showcase by Buffalo. On December 1, 2024, the Buffalo Bills defeated the San Francisco 49ers 35 to 10 at Highmark Stadium in snowy Orchard Park, New York. The final score was significant, but the player statistics reveal exactly why Buffalo controlled the matchup from start to finish.
This game featured standout performances from Josh Allen, James Cook, and Buffalo’s opportunistic defense. On the San Francisco side, injuries and turnovers prevented the 49ers from finding any rhythm. If you want to understand who dominated, who struggled, and which numbers mattered most, this detailed breakdown covers everything you need to know.
Game Overview
| Category | Result |
| Final Score | Buffalo Bills 35, San Francisco 49ers 10 |
| Date | December 1, 2024 |
| Venue | Highmark Stadium, Orchard Park, New York |
| Weather | Snowy conditions |
| Bills Record After Game | 10 and 2 |
| 49ers Record After Game | 5 and 7 |
The snowy conditions made execution difficult, but Buffalo handled the weather far better. Their offense remained efficient, and their defense forced mistakes at key moments.
49ers vs Buffalo Bills Match Player Stats: Key Takeaways
The 49ers vs buffalo bills match player stats highlight five decisive factors:
- Josh Allen accounted for passing, rushing, and receiving touchdowns.
- James Cook broke the game open with a 65-yard touchdown run.
- Buffalo committed zero turnovers.
- San Francisco turned the ball over three times.
- The Bills converted all four red-zone trips into touchdowns.
These numbers explain why Buffalo dominated despite modest passing yard totals.
Final Team Stats Comparison
| Stat | 49ers | Bills |
| Total Yards | 239 | 372 |
| First Downs | 15 | 20 |
| Turnovers | 3 | 0 |
| Third Down Efficiency | 3 of 10 | 6 of 12 |
| Time of Possession | 26:33 | 33:27 |
| Red Zone Efficiency | 1 of 3 | 4 of 4 |
| Sacks Allowed | 2 | 0 |
Buffalo was cleaner, more efficient, and more explosive in every critical area.
Buffalo Bills Player Stats
Josh Allen Performance
Josh Allen delivered one of the most memorable performances of his career.
| Passing Stats | Total |
| Completions/Attempts | 13/17 |
| Passing Yards | 148 |
| Passing Touchdowns | 2 |
| Interceptions | 0 |
| Passer Rating | 141.3 |
| Rushing Stats | Total |
| Carries | 3 |
| Rushing Yards | 18 |
| Rushing Touchdowns | 1 |
| Receiving Stats | Total |
| Receptions | 1 |
| Receiving Yards | 7 |
| Receiving Touchdowns | 1 |
Allen became the first quarterback in NFL history to record a passing touchdown, rushing touchdown, and receiving touchdown in the same game. His receiving score came on a designed lateral play from Amari Cooper.
James Cook Stats
James Cook was the most explosive runner on the field.
| Stat | Total |
| Carries | 14 |
| Rushing Yards | 107 |
| Yards Per Carry | 7.6 |
| Touchdowns | 1 |
| Long Run | 65 yards |
Cook’s long touchdown early in the second quarter shifted momentum heavily in Buffalo’s favor.
Ray Davis Stats
Ray Davis added an early touchdown.
| Stat | Total |
| Rushing Touchdowns | 1 |
| Touchdown Run | 5 yards |
Bills Receiving Leaders
| Player | Receptions | Yards | TD |
| Mack Hollins | 2 | 27 | 1 |
| Amari Cooper | 1 | 7 | 1 pass on lateral play |
| Khalil Shakir | 3 | Key chain-moving catches | 0 |
Buffalo Defensive Standouts
Buffalo’s defense consistently pressured Brock Purdy and forced critical turnovers.
Top contributors included:
- Terrel Bernard
- Greg Rousseau
- Taylor Rapp
Their collective effort kept San Francisco from sustaining drives.
San Francisco 49ers Player Stats
Brock Purdy Stats
Brock Purdy returned from injury but never found a consistent rhythm.
| Passing Stats | Total |
| Completions/Attempts | 11/18 |
| Passing Yards | 94 |
| Passing Touchdowns | 0 |
| Interceptions | 0 |
| Sacks Taken | 2 |
Purdy was held under 100 passing yards, which is extremely rare for the 49ers offense.
Christian McCaffrey Stats
Christian McCaffrey started well before exiting with a knee injury.
| Stat | Total |
| Carries | 7 |
| Rushing Yards | 53 |
| Receptions | 2 |
| Receiving Yards | 14 |
Before his injury, McCaffrey averaged 7.6 yards per carry and looked like San Francisco’s best offensive weapon.
Isaac Guerendo Stats
Isaac Guerendo provided the lone touchdown.
| Stat | Total |
| Rushing Touchdowns | 1 |
| Touchdown Run | 15 yards |
Jauan Jennings Stats
Jauan Jennings led the team in receiving.
| Stat | Total |
| Receiving Yards | 56 |
George Kittle Stats
George Kittle was largely contained by Buffalo’s defense and never became a game-changing factor.
Quarter-by-Quarter Scoring Summary
First Quarter
- Jake Moody 33-yard field goal
- Ray Davis 5-yard rushing touchdown
Bills lead 7 to 3.
Second Quarter
- James Cook 65-yard rushing touchdown
- Josh Allen to Mack Hollins for 7-yard touchdown
Bills lead 21 to 3 at halftime.
Third Quarter
- Josh Allen receiving touchdown
- Isaac Guerendo 15-yard rushing touchdown
Bills lead 28 to 10.
Fourth Quarter
- Josh Allen 8-yard rushing touchdown
Final score: Bills 35, 49ers 10.
How Josh Allen Took Over the Game
Watching this matchup, one thing stood out immediately: Josh Allen was in total control. He did not need 300 passing yards to dominate. Instead, he made decisive throws, avoided sacks, and added unique scoring plays that kept San Francisco off balance.
What made Allen’s performance elite:
- High efficiency with 13 completions on 17 attempts
- Zero turnovers
- Three different types of touchdowns
- Complete command in difficult weather
This is exactly what MVP-level quarterbacks do. They adapt to the conditions and make winning plays.
Why the 49ers Struggled
The 49ers entered the game needing a statement win, but several issues derailed them.
1. Turnovers
Three turnovers in snowy conditions are almost impossible to overcome.
2. McCaffrey Injury
San Francisco lost its most dynamic weapon early.
3. Limited Passing Game
Purdy threw for only 94 yards.
4. Defensive Breakdowns
The 49ers gave up multiple explosive touchdowns.
5. Poor Red-Zone Execution
They scored just one touchdown in three red-zone opportunities.
Most Important Player Stats That Decided the Game
The 49ers vs buffalo bills match player stats become especially revealing when you focus on these numbers:
| Player | Key Stat |
| Josh Allen | 4 total touchdowns |
| James Cook | 107 rushing yards |
| Brock Purdy | 94 passing yards |
| Christian McCaffrey | Left early with injury |
| Bills Defense | 3 takeaways |
| 49ers Offense | 239 total yards |
These are the statistics that changed the outcome.
Advanced Statistical Insights
Efficiency Matters More Than Volume
Buffalo did not post huge yardage totals, but their efficiency was outstanding.
- 4 for 4 in the red zone
- 0 turnovers
- 141.3 passer rating from Allen
Explosive Plays Win Games
James Cook’s 65-yard touchdown run was the game’s turning point.
Field Position and Possession
Buffalo controlled the ball for nearly seven minutes longer, limiting San Francisco’s opportunities.
Historical Significance
This matchup will be remembered for Josh Allen’s rare stat line. Very few games combine passing, rushing, and receiving touchdowns from one quarterback. In adverse weather against a talented opponent, Allen delivered a performance that strengthened his MVP case.
Official game data is available from Pro Football Reference.
Fantasy Football Impact
For fantasy managers, this game had major implications.
Winners
- Josh Allen
- James Cook
- Bills Defense/Special Teams
Disappointments
- Brock Purdy
- Christian McCaffrey due to injury
- George Kittle
Lessons for Fantasy Managers
Weather, turnovers, and injuries can dramatically change projections. This game was a reminder to monitor all three factors before kickoff.
Betting Insights From the Stats
The 49ers vs buffalo bills match player stats also explain why Buffalo covered comfortably.
- Bills won by 25 points
- Josh Allen exceeded touchdown expectations
- James Cook smashed rushing props
- San Francisco offensive unders were easy winners
Stat-driven bettors could see Buffalo’s edge in turnover margin and red-zone efficiency.
What This Game Meant for Buffalo
The victory improved Buffalo to 10 and 2 and clinched another AFC East title. More importantly, it showed the Bills could win in multiple ways:
- Efficient passing
- Dominant rushing
- Creative play design
- Opportunistic defense
That balance is what makes a true Super Bowl contender.
What This Game Meant for San Francisco
The loss dropped San Francisco to 5 and 7 and put its playoff hopes in serious danger.
Major concerns included:
- Injuries to key stars
- Turnover issues
- Inconsistent offensive line play
- Lack of explosive passing plays
The roster remained talented, but the margin for error was gone.
Lessons Coaches Can Take From This Matchup
For Buffalo
- Lean into Allen’s versatility
- Continue using Cook as a featured weapon
- Maintain aggressive red-zone play-calling
For San Francisco
- Protect Purdy better
- Reduce turnovers
- Preserve McCaffrey’s health
FAQs
Who had the best performance in the 49ers vs Bills game?
Josh Allen had the standout performance with two passing touchdowns, one rushing touchdown, and one receiving touchdown.
What were Josh Allen’s final stats?
Allen completed 13 of 17 passes for 148 yards and two touchdowns, rushed for one score, and caught a touchdown pass.
How many rushing yards did James Cook have?
James Cook ran for 107 yards and one touchdown.
What were Brock Purdy’s stats?
Purdy completed 11 of 18 passes for 94 yards with no touchdowns.
Did Christian McCaffrey get injured?
Yes. McCaffrey left the game in the second quarter with a knee injury after totaling 67 yards from scrimmage.
What was the final score?
The Buffalo Bills defeated the San Francisco 49ers 35 to 10.
Also read Buffalo Bills vs Colts Match
Conclusion
The 49ers vs buffalo bills match player stats reveal a game defined by efficiency, explosiveness, and ball security. Josh Allen produced one of the most unique quarterback performances in recent NFL history, James Cook added game-breaking speed, and Buffalo’s defense forced San Francisco into costly mistakes.
For the 49ers, the numbers show how difficult it is to win when turnovers pile up and key players leave injured. For the Bills, this matchup was a statement that they were one of the NFL’s most complete teams.
Whether you are a football analyst, fantasy manager, or dedicated fan, the stats from this game offer a clear lesson: the teams that protect the football and capitalize in the red zone usually control the scoreboard.
